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GLP-1 receptor agonists mimic gut hormones to curb appetite and slow digestion, a mechanism driving the success of therapies from Novo Nordisk (Ozempic for diabetes and Wegovy for weight loss) and Lilly (Mounjaro for diabetes and Zepbound for weight loss)

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Consequently, malnutrition in COPD is linked to diminished health-related QoL, worse prognosis and outcomes, as well as elevated healthcare use and costs [19,20,21,22]

A considerable amount of research has been dedicated to the various disorders associated with disturbed carnitine and acetylcarnitine homeostasis, but the pharmacokinetics of acetylcarnitine have mostly been studied in healthy subjects and very few studies report carnitine pharmacokinetics in patient groups, most of which are dedicated to studies in hemodialysis patients [108]